Rank-ordered formulation candidates
Fully specified — every excipient, concentration and pH stated — and ordered so the bench knows what to make first.
Engagement one
We run the design
For a programme that needs a defensible formulation strategy now. You send a primary sequence and a set of product targets; we return the ranked candidates and the bench plan to confirm them.
Best when the question is one molecule, and the answer is needed this quarter.
Engagement one
Accelerated Formulation Design
- The full agent system runs on your molecule, operated by our scientists
- A primary sequence and product targets are the whole intake
- A scored candidate space, ranked into a priority, contingency and exploratory set
- A statistically designed DoE plan and the SOPs to execute it
- Typically two weeks from complete intake to the package
- Every outcome vests in you; your materials are destroyed at close-out
Deliverables
What lands on your bench, and in your filing.
One structured, statistically coherent dataset — not a series of disconnected screening reports.
Confidence for every candidate
Each candidate carries its own confidence, so prioritisation is a stated judgement rather than an implicit one.
Bench-level SOPs
The standard operating procedures needed to make the candidates, written for the people who will run them.
A deliberately defined design space
One structured, statistically coherent dataset instead of a series of disconnected screening reports — which is what later comparability, scale-up and lifecycle changes rest on.
How it works
From sequence to a short list worth making.
The design space is explored computationally first. The bench is used to confirm.
Inputs
A primary sequence and a set of product targets — concentration, presentation, device, and the constraints the program already carries. Nothing more is required to start.
Computational exploration
The design space — buffer and pH, sugars and polyols, amino acid excipients, ionic strength, surfactant, chelators and antioxidants — is explored computationally rather than sampled sparsely at the bench.
Ranked candidates
A rank-ordered, fully specified set of formulation candidates, with confidence attached to each, delivered as one structured and statistically coherent dataset.
Bench confirmation
Bench-level standard operating procedures for making each candidate, so the laboratory runs a focused confirmatory exercise instead of an open-ended search.
The service
What a partner actually receives.
Starting from nothing more than a primary sequence and a set of product targets, Uplizd delivers a rank-ordered, fully specified set of formulation candidates, and the bench-level standard operating procedures needed to make them — typically within two weeks.
The usual path
An open-ended empirical search
- Two to three development quarters, or longer
- Grams of precious drug substance consumed
- A broad, unguided screening matrix
- A series of disconnected screening reports
With Uplizd
A focused confirmatory exercise
- A ranked strategy typically within two weeks
- Material spent confirming, not searching
- A prioritized set of conditions
- One structured, statistically coherent dataset
For Uplizd’s partners, this converts formulation development from an open-ended empirical search into a focused confirmatory exercise.
Business impact
The benefit shows up in three places.
Speed, cost, and the quality of the knowledge your programme carries forward.
Speed
Weeks rather than quarters.
A defensible, ranked formulation strategy is available in weeks rather than quarters, which pulls in the timing of tox lots, stability starts, first-in-human enabling material, and eventually CMC sections of regulatory filings.
- Tox lots scheduled earlier
- Stability starts brought forward
- First-in-human enabling material unblocked
- CMC sections written against a defined design space
Cost
A prioritized set, not a broad matrix.
Screening effort is concentrated on a prioritized set of conditions instead of a broad, unguided matrix. This reduces FTE time, analytical load, and the quantity of purified drug substance consumed — usually the scarcest and most expensive input at early stage.
- Less FTE time at the bench
- Lower analytical load
- Less purified drug substance consumed
- Effort spent confirming, not searching
Efficiency and knowledge quality
One coherent dataset, not scattered reports.
The partner receives a single, structured, statistically coherent dataset with confidence for every candidate, rather than a series of disconnected screening reports. The design space is defined deliberately, which strengthens later comparability, scale-up and lifecycle changes.
- Confidence attached to every candidate
- One structured dataset, not scattered reports
- A deliberately defined design space
- Stronger comparability, scale-up and lifecycle changes
Put the specialists on your molecule.
Engagements begin with a conversation and a signed agreement; access credentials follow. Send a primary sequence and your product targets, or tell us what you want built, and we will reply from a person.